Afucosylated antibodies
Afucosylated antibodies are recombinant antibodies with low fucose content that demonstrate higher ADCC (Antibody-Dependent Cellular Cytotoxicity). Examples of diseases where afucosylated antibodies are applied to include cancer, autoimmune diseases, and genetic disorders. Find here exciting contributions to these topics.
Articles about Afucosylated antibodies (8)
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Therapeutic antibodies: afucosylated antibodies with enhanced antibody-dependent cellular cytotoxicity (ADCC)
Therapeutic antibodies are the fastest-growing class of biological drugs. Their ability to interact with specific targets means they can be employed for a range of diseases, including cancer, autoimmune and infectious diseases.
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How are afucosylated antibodies developed?
Afucosylated antibodies are promising tools in the fight against several diseases. But how are they developed? That is what we are going to find out in this article.
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Applications of afucosylated antibodies
Afucosylated antibodies are either studied or already used in various fields of application. In this article, we will explore some of them.
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Afucosylated recombinant antibodies
Generally speaking, antibodies of any kind, including recombinant and afucosylated antibodies, are Y-shaped proteins produced by the human body. As they are able to identify and neutralize foreign objects – in other words viruses – they play a major contributing role in keeping our body and immune system healthy.
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Glycosylation of proteins
Glycosylation is an essential biochemical process, which is also used in the production of recombinant proteins. In this article, we will explore it in more detail.
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Afucosylation simply explained
Afucosylation stands as a critical phenomenon with far-reaching implications. This article aims to provide an exploration of afucosylation, shedding light on its significance and its role in various scientific fields.
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Antibody glycoengineering: pushing forward biotechnology
The importance of glycosylation patterns (sugar sequences) on proteins and their glycobiology have been intensely investigated in recent years, and the deeper understanding spawned novel applications that push biotechnology forward. vice offerings in the field of glyco-engineering.
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Antibody-Dependent Cellular Cytotoxicity (ADCC) – definition, mechanism & application
Antibody-dependent cellular cytotoxicity is a key process of the immune system’s arsenal to ward off cancerous cells and infections. We show you important definitions and the ADCC mechanism and key facts on ADCC antibodies in this post.