Antibody Journal
Articles about Antibody Journal (0)
-
Antibody Production simply explained
In order to provide life sciences with highly valuable antibodies, they have to be produced according to complex processes. Here, we provide you an introduction to the field of antibody production.
-
Antibody production in CHO cells: Advantages & Disadvantages
CHO cells are an essential tool in antibody production. But why should one choose CHO cells instead of other expression systems? Read more to find out!
-
Purification of His-tagged proteins
Proteins tagged with 4-10 histidine (His) residues can be purified using Immobilized Metal Affinity Chromatography (IMAC). This technique utilizes imidazole rings present on histidine side chains to non-covalently bind to the positively charged metal ions within an IMAC resin. IMAC purification can be used to purify proteins in their native conformation as well as under denaturing conditions.
-
Differences between monoclonal antibodies and recombinant monoclonal antibodies
There are some major differences between monoclonal and recombinant monoclonal antibodies – discover the most important ones in this article!
-
Bispecific Antibodies: Commercial Successes and Research Feasibility
In the past 10 years, the use of bispecific antibodies – proteins capable of engaging two targets simultaneously – has become a key focus area for the industry. Read all about their success and research feasibility in this article.
-
Antibodies in medicine and research: Definition, function and formats
Antibodies play a significant role in modern medicine and research and have allowed huge leaps in the treatment of various medical conditions – but why, and how do they work? Find out in the course of this article!
-
In vivo vs. in vitro antibody production
In vivo or in vitro – which is the better way for antibody production? The issue is highly discussed among experts, and historically, they both have had their merit. This article will show the main differences, advantages and disadvantages of the two approaches.
-
Fc Silenced Antibody – Therapeutic antibodies with reduced side effect profile
One of the most exciting recent developments in the sector is the engineering of antibodies’ fragment crystallizable (Fc region). Fc engineering entails the optimization of recombinant monoclonal antibodies, anticancer bispecific antibodies and Fc fusion proteins by means of modifications at specific residues to enhance performance in their intended applications. Read more!
-
Antibody glycoengineering: pushing forward biotechnology
The importance of glycosylation patterns (sugar sequences) on proteins and their glycobiology have been intensely investigated in recent years, and the deeper understanding spawned novel applications that push biotechnology forward. vice offerings in the field of glyco-engineering.
-
Polyclonal vs monoclonal vs recombinant antibodies – a comparison
Antibody generation appears like a vast and daunting field. Terms such as polyclonal, monoclonal and recombinant make it seem to be overly technical. In this read, we show you a comparison of these antibody types.
